Publications

Timothy P. Spann, Ph. D.

Shumaker D.K., Lopez-Soler R.I., Adams S.A., Herrmann H., Moir R.D., Spann T.P., Goldman R.D., (2005). Functions and dysfunctions of the nuclear lamin Ig-fold domain in nuclear assembly, growth, and Emery-Dreifuss muscular dystrophy. Proc. Natl. Acad. Sci. U.S.A. 102 (43): 15494-9.
Spann T.P., Goldman A.E., Wang C., Huang S. and Goldman R.D. (2002). Alteration of lamin organization inhibits RNA polymerase II dependent transcription. J. Cell Biol. 156: 605-608.
Goldman R.D., Gruenbaum Y., Moir R.D., Shumaker D. K., Spann T.P. (2002). Nuclear lamins: building blocks of nuclear architecture. Genes Dev. 16 (5): 533-47.
Lopez-Soler RI, Moir RD, Spann TP, Stick R, Goldman RD (2001). A role for nuclear lamins in nuclear envelope assembly. J Cell Biol.. 154(1):61-70.
Moir R.D. and Spann T.P. (2001). The structure and function of nuclear lamins: implications for disease. CMLS 58: 1748-1757.
Moir R.D., Spann T.P., Herrmann, H. and Goldman, R. D. (2000). Disruption of nuclear lamin organization blocks the elongation phase of DNA replication. J. Cell Biol. 149: 1179-1192.
Moir R.D., Spann T.P., Lopez-Soler R.I., Yoon M., Goldman A.E., Khuon S. and Goldman R.D. (2000). The dynamics of the nuclear lamins during the cell cycle: relationship between structure and function. Special Issue, J. Structural Biol. 129 (3): 324-334.
Moir R.D., Spann T.P., and Goldman R.D. (1999). The Nuclear Lamins: Type V intermediate filament proteins. A Guidebook to the Cytoskeleton (editors, Vale and Kreis). Oxford University Press. Second Edition, p. 324-326.
Spann T.P., Moir R.D., Goldman A.E., Stick R., and Goldman R.D. (1997). Disruption of the nuclear lamin organization alters the distribution of replication factors and inhibits DNA synthesis. J. Cell Biol., 136: 1201-1212.
Spann T.P., Brock D.A., and Gomer R.H. (1997). Antisense technology: A practical approach. Chapter: Shotgun antisense mutagenesis. Eds, C. Lichtenstein and W. Nellen (The Practical Approach Series. Series Editor, B.D. Hames). Pgs. 273-279.
Brock D.A., Buczyndki G., Spann T.P., Wood S.A., Cardelli J., and Gomer, R.H., (1996). A Dictyostelium mutant with defective aggregate size determination. Dev. 122 (9): 2569-2578.
Wood S.A., Ammann R.R., Brock D.A., Li L., Spann T.P. and Gomer R.H., (1996). RtoA links initial cell type choice to the cell cycle in Dictyostelium. Dev. 122 (11): 3677-3685.
Spann T.P., Brock D.A., Lindsey D.F., Wood S.A., and Gomer R.H., (1996). Mutagenesis and gene identification in Dictyostelium by shotgun antisense. PNAS 93 (10): 5003-5007.
Moir R.D., Spann T.P., and Goldman R.D., (1995). The dynamic properties and possible functions of nuclear lamins. Inter. Rev. Cytology, 162B: 141-182.
Spann T.P., (1991). The binding of matrix-associated DNA regions (MARs) to nuclear matrices: A partial purification and characterization of the proteins mediating this specific interaction. Thesis. University of California, San Diego.
Newport J. and Spann T.P., (1987). Disassembly of the nucleus in mitotic extracts: Membrane vesicularization, lamin disassembly, and chromosome condensation are independent processes. Cell 48: 219-230.
Newport J., Spann T.P., Kanki J. and Forbes D., (1985). The role of mitotic factors in regulating the timing of the midblastula transition in Xenopus. Cold Spring Harbor Symposia on Quantitative Biology Vol. L: 651-655.


Back to Profile	Publications Timothy P. Spann, Ph. D. Shumaker D.K., Lopez-Soler R.I., Adams S.A., Herrmann H., Moir R.D., Spann T.P., Goldman R.D., (2005). Functions and dysfunctions of the nuclear lamin Ig-fold domain in nuclear assembly, growth, and Emery-Dreifuss muscular dystrophy. Proc. Natl. Acad. Sci. U.S.A. 102 (43): 15494-9. Spann T.P., Goldman A.E., Wang C., Huang S. and Goldman R.D. (2002). Alteration of lamin organization inhibits RNA polymerase II dependent transcription. J. Cell Biol. 156: 605-608. Goldman R.D., Gruenbaum Y., Moir R.D., Shumaker D. K., Spann T.P. (2002). Nuclear lamins: building blocks of nuclear architecture. Genes Dev. 16 (5): 533-47. Lopez-Soler RI, Moir RD, Spann TP, Stick R, Goldman RD (2001). A role for nuclear lamins in nuclear envelope assembly. J Cell Biol.. 154(1):61-70. Moir R.D. and Spann T.P. (2001). The structure and function of nuclear lamins: implications for disease. CMLS 58: 1748-1757. Moir R.D., Spann T.P., Herrmann, H. and Goldman, R. D. (2000). Disruption of nuclear lamin organization blocks the elongation phase of DNA replication. J. Cell Biol. 149: 1179-1192. Moir R.D., Spann T.P., Lopez-Soler R.I., Yoon M., Goldman A.E., Khuon S. and Goldman R.D. (2000). The dynamics of the nuclear lamins during the cell cycle: relationship between structure and function. Special Issue, J. Structural Biol. 129 (3): 324-334. Moir R.D., Spann T.P., and Goldman R.D. (1999). The Nuclear Lamins: Type V intermediate filament proteins. A Guidebook to the Cytoskeleton (editors, Vale and Kreis). Oxford University Press. Second Edition, p. 324-326. Spann T.P., Moir R.D., Goldman A.E., Stick R., and Goldman R.D. (1997). Disruption of the nuclear lamin organization alters the distribution of replication factors and inhibits DNA synthesis. J. Cell Biol., 136: 1201-1212. Spann T.P., Brock D.A., and Gomer R.H. (1997). Antisense technology: A practical approach. Chapter: Shotgun antisense mutagenesis. Eds, C. Lichtenstein and W. Nellen (The Practical Approach Series. Series Editor, B.D. Hames). Pgs. 273-279. Brock D.A., Buczyndki G., Spann T.P., Wood S.A., Cardelli J., and Gomer, R.H., (1996). A Dictyostelium mutant with defective aggregate size determination. Dev. 122 (9): 2569-2578. Wood S.A., Ammann R.R., Brock D.A., Li L., Spann T.P. and Gomer R.H., (1996). RtoA links initial cell type choice to the cell cycle in Dictyostelium. Dev. 122 (11): 3677-3685. Spann T.P., Brock D.A., Lindsey D.F., Wood S.A., and Gomer R.H., (1996). Mutagenesis and gene identification in Dictyostelium by shotgun antisense. PNAS 93 (10): 5003-5007. Moir R.D., Spann T.P., and Goldman R.D., (1995). The dynamic properties and possible functions of nuclear lamins. Inter. Rev. Cytology, 162B: 141-182. Spann T.P., (1991). The binding of matrix-associated DNA regions (MARs) to nuclear matrices: A partial purification and characterization of the proteins mediating this specific interaction. Thesis. University of California, San Diego. Newport J. and Spann T.P., (1987). Disassembly of the nucleus in mitotic extracts: Membrane vesicularization, lamin disassembly, and chromosome condensation are independent processes. Cell 48: 219-230. Newport J., Spann T.P., Kanki J. and Forbes D., (1985). The role of mitotic factors in regulating the timing of the midblastula transition in Xenopus. Cold Spring Harbor Symposia on Quantitative Biology Vol. L: 651-655.